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Michael J Seckl Selected Research

Gestational Trophoblastic Disease (Trophoblastic Neoplasms, Gestational)

1/2022ATR and CDK4/6 inhibition target the growth of methotrexate-resistant choriocarcinoma.
10/2021Diagnosis and management of gestational trophoblastic disease: 2021 update.
1/2021Predictors for single-agent resistance in FIGO score 5 or 6 gestational trophoblastic neoplasia: a multicentre, retrospective, cohort study.
1/2021Uterine artery pulsatility index and serum BMP-9 predict resistance to methotrexate therapy in gestational trophoblastic neoplasia: A cohort study.
1/2020Following chemotherapy for gestational trophoblastic neoplasia, do residual lung lesions increase the risk of relapse?
1/2020Validation of an online tool for early prediction of the failure-risk in gestational trophoblastic neoplasia patients treated with methotrexate.
10/2019When to stop human chorionic gonadotrophin (hCG) surveillance after treatment with chemotherapy for gestational trophoblastic neoplasia (GTN): A national analysis on over 4,000 patients.
1/2019Is there uniformity in definitions and treatment of gestational trophoblastic disease in Europe?
10/2018Update on the diagnosis and management of gestational trophoblastic disease.
4/2018Power Doppler Quantification in Assessing Gestational Trophoblastic Neoplasia.
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Michael J Seckl Research Topics

Disease

29Gestational Trophoblastic Disease (Trophoblastic Neoplasms, Gestational)
01/2022 - 06/2002
25Neoplasms (Cancer)
10/2021 - 05/2002
12Lung Neoplasms (Lung Cancer)
01/2021 - 06/2008
10Choriocarcinoma
06/2022 - 12/2003
9Small Cell Lung Carcinoma (Small Cell Lung Cancer)
05/2017 - 04/2002
8Hydatidiform Mole (Molar Pregnancy)
02/2019 - 07/2004
6Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2019 - 03/2010
6Trophoblastic Neoplasms (Trophoblastic Tumor)
02/2016 - 03/2002
5Neoplasm Metastasis (Metastasis)
01/2021 - 05/2002
4Teratoma (Teratoid Tumor)
01/2021 - 07/2008
3Brain Neoplasms (Brain Tumor)
10/2021 - 06/2002
2Carcinogenesis
11/2017 - 08/2006
2Infertility (Sterility)
05/2016 - 07/2007
2Leukemia
02/2015 - 01/2011
2Testicular Neoplasms (Testicular Cancer)
04/2013 - 11/2006
2Hemorrhage
07/2012 - 03/2002
2Vascular Malformations
07/2012 - 03/2002
2Germ Cell and Embryonal Neoplasms (Germ Cell Tumor)
07/2010 - 10/2006
1Urinary Bladder Neoplasms (Bladder Cancer)
01/2021
1Pulmonary Veno-Occlusive Disease (Veno Occlusive Disease, Pulmonary)
03/2019
1Pulmonary Arterial Hypertension
03/2019
1Uterine Perforation
04/2018
1Dysgerminoma
01/2018
1Disease Progression
05/2017
1Breast Neoplasms (Breast Cancer)
01/2016
1Melanoma (Melanoma, Malignant)
02/2015
1Mouth Neoplasms (Oral Cancer)
02/2015
1Meningioma (Meningiomas)
02/2015
1Second Primary Neoplasms (Neoplasms, Second)
02/2015
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
03/2014

Drug/Important Bio-Agent (IBA)

16Chorionic Gonadotropin (Human Chorionic Gonadotropin)FDA LinkGeneric
10/2021 - 05/2002
11Methotrexate (Mexate)FDA LinkGeneric
06/2022 - 09/2007
7Etoposide (VP 16)FDA LinkGeneric
08/2019 - 11/2003
5DNA (Deoxyribonucleic Acid)IBA
07/2019 - 12/2011
4Cisplatin (Platino)FDA LinkGeneric
08/2019 - 11/2009
4Vincristine (Oncovin)FDA LinkGeneric
01/2019 - 09/2007
4Cyclophosphamide (Cytoxan)FDA LinkGeneric
01/2019 - 09/2007
4Dactinomycin (Actinomycin)FDA LinkGeneric
01/2019 - 09/2007
4Proteins (Proteins, Gene)FDA Link
11/2017 - 02/2009
4Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
01/2011 - 04/2002
3Pharmaceutical PreparationsIBA
01/2021 - 11/2017
3Phosphotransferases (Kinase)IBA
01/2021 - 03/2010
2EnzymesIBA
01/2019 - 01/2017
2Indicators and Reagents (Reagents)IBA
04/2018 - 07/2010
2Messenger RNA (mRNA)IBA
11/2017 - 02/2012
2Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
05/2017 - 06/2008
2Apoptosis Regulatory ProteinsIBA
11/2014 - 01/2011
2Biomarkers (Surrogate Marker)IBA
03/2014 - 03/2010
2Protein Isoforms (Isoforms)IBA
09/2013 - 01/2013
2Phosphatidylinositols (Phosphatidylinositol)IBA
01/2013 - 05/2007
2Opiate AlkaloidsIBA
07/2012 - 03/2002
2Fibroblast Growth Factors (Fibroblast Growth Factor)IBA
01/2011 - 11/2003
2Janus KinasesIBA
01/2011 - 01/2011
2Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA
12/2010 - 11/2009
2TOR Serine-Threonine KinasesIBA
03/2010 - 02/2009
1ProteomeIBA
01/2022
1Cyclin-Dependent Kinase 4IBA
01/2022
1Growth Differentiation Factor 2IBA
01/2021
1Anti-Bacterial Agents (Antibiotics)IBA
01/2021
1Immune Checkpoint InhibitorsIBA
01/2021
1trovafloxacinIBA
01/2021
1PlatinumIBA
08/2019
1Tyrosine Kinase InhibitorsIBA
03/2019
1Mitomycin (Mitomycin-C)FDA LinkGeneric
03/2019
1Paclitaxel (Taxol)FDA LinkGeneric
01/2019
1Chir 99021IBA
01/2019
1Glycogen Synthase (Synthase I)IBA
01/2019
1Dasatinib (BMS 354825)FDA Link
06/2018
1src-Family KinasesIBA
06/2018
1pembrolizumabIBA
11/2017
1Pravastatin (Pravachol)FDA LinkGeneric
05/2017
1Carboplatin (JM8)FDA LinkGeneric
05/2017
1Interferon Type IIBA
01/2017
1Mitogen-Activated Protein KinasesIBA
01/2017
1Cystine (L-Cystine)IBA
01/2017
1fludarabineIBA
01/2017
1Hormones (Hormone)IBA
05/2016
1Circulating Tumor DNAIBA
02/2016
1Cell-Free Nucleic AcidsIBA
02/2016
1RNA (Ribonucleic Acid)IBA
01/2016
13' Untranslated Regions (3' UTR)IBA
01/2016
1Glutathione (Reduced Glutathione)IBA
01/2016
1Erlotinib Hydrochloride (CP 358,774)FDA Link
01/2016
1ErbB Receptors (EGF Receptor)IBA
01/2016
1Leucovorin (Folinic Acid)FDA Link
02/2015
1KynurenineIBA
03/2014
1Methionine (L-Methionine)FDA Link
03/2014
1Tryptophan (L-Tryptophan)FDA Link
03/2014
1Glycogen Synthase Kinase 3IBA
01/2014
1Protein Kinases (Protein Kinase)IBA
01/2014
1Complement System Proteins (Complement)IBA
06/2013

Therapy/Procedure

31Drug Therapy (Chemotherapy)
10/2021 - 05/2002
9Therapeutics
01/2022 - 08/2006
3Radiotherapy
10/2021 - 10/2018
2Induction Chemotherapy
10/2021 - 10/2018
2Adjuvant Chemotherapy
01/2021 - 01/2020
2Aftercare (After-Treatment)
10/2019 - 01/2017
2Combination Drug Therapy (Combination Chemotherapy)
02/2015 - 09/2007
2Uterine Artery Embolization
07/2012 - 03/2002
1Stem Cell Transplantation
01/2017